Raising Money for
2010 MRF Research Grantee
Completing their study in 2013, Dr. Aylward and Dr. Powers compared the baseline impact of migraine on teens’ functioning with changes at 6 months after starting biobehavioral treatment—treatment involving preventive medication and lifestyle education. There were significant improvements in functioning at the 6-month visit, but not for all. This is important evidence that a treatment program combining preventive medication and lifestyle education can be helpful for teen sufferers.
FINAL REPORT: The Multidimensional Impact of Migraine in Adolescents Presenting to Specialty Care
Published in JAMA, December 2013.
The functional consequences of adolescent migraine can be widespread and have a negative effect on many aspects of normal daily life. To examine this, a longitudinal, multi-method and multifaceted assessment of migraine was conducted in a sample of adolescents presenting to a pediatric headache center. The purpose was to identify and compare the baseline impact of migraine on physical, emotional, social, and school functioning with changes at six months after starting biobehavioral treatment involving preventive medication and lifestyle education. One-hundred and fifteen adolescents participated in the six-month study. Overall, physical functioning at baseline suggested moderate disability. However, there was significant improvement in functioning at the six-month visit.
In addition, a mobile application (iMigraine) was developed by a team of researchers, clinicians, and technology experts to enable adolescents to electronically enter and wirelessly transmit data about headache events and associated symptoms. Participants were prompted to assess their condition daily using the iMigraine app. They reported having a headache on 49% of days they completed at least one prompt. On average, each participant reported having 23 headaches during the 45 day period.
Hypothesis vs. Findings
The working hypothesis of the study was that the experience of migraine in adolescence would be associated with measurable negative impact on physical (including sleep quality), school, emotional, social, and family functioning. Overall, decreased physical and psychosocial functioning were evident in a number of participants in the study. They showed significant improvements in migraine-associated disability at the six-month follow-up visit. This improvement was also associated with changes in other areas, such as emotional functioning and sleep.